A tight interplay between platelet activation and mitochondrial DNA release promotes platelet storage lesion in platelet concentrates.

Kamand HaeriShahram SamieePeyman BeigiSmerdis HajatiMohammad Reza Deyhim

Published in: Vox sanguinis (2024)

The interplay between platelet activation and mtDNA release in promoting PSL in PCs may serve as a promising target for future research on applying additive solutions and evaluating the quality of PCs to improve transfusion and clinical outcomes.

Keyphrases

mitochondrial dna
copy number
blood brain barrier
gene expression
dna methylation