Login / Signup

Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus.

Meera SrikrishnaWoosung SeoAnna ZettergrenSilke KernDaniel CantréFlorian GesslerHouman SotoudehJakob SeidlitzJoshua D BernstockLars-Olof WahlundErik WestmanIngmar SkoogJohan VirhammarDavid FällmarMichael Schöll
Published in: medRxiv : the preprint server for health sciences (2024)
CTVMs derived through deep learning, show potential for assessing and quantifying morphological features in hydrocephalus. Critically, these measures performed comparably to gold-standard neuroradiology assessments in distinguishing iNPH from healthy controls, even in the presence of intraventricular shunt catheters. Accordingly, such an approach may serve to improve the radiological evaluation of iNPH diagnosis/monitoring (i.e., treatment responses). Since CT is much more widely available than MRI, our results have considerable clinical impact.
Keyphrases