A novel fluorescent probe for efficient detection of fluoride ions in living animal and plant tissues.
Jun ChenMaoting QuJiahao ZhangYongxue YaoXinyu PeiWen WuShuchen PeiPublished in: Analytical methods : advancing methods and applications (2024)
This work presents the design and synthesis of a new fluorescent probe IF-Br-F for the specific detection of fluoride ions. The IF-Br-F probe has excellent fluorescence properties, and the mechanism of the probe response to fluoride ions was successfully verified via HRMS and DFT calculations. IF-Br-F has high sensitivity and low detection limit (5.82 × 10 -7 mol L -1 ) and successfully detects fluoride ions in actual water samples. The probe can be applied to fluorescence imaging of zebrafish, cells, and Arabidopsis roots and exhibits low cytotoxicity and good biocompatibility.
Keyphrases
- living cells
- fluorescent probe
- quantum dots
- drinking water
- fluorescence imaging
- single molecule
- loop mediated isothermal amplification
- aqueous solution
- real time pcr
- label free
- density functional theory
- induced apoptosis
- photodynamic therapy
- gene expression
- water soluble
- molecular docking
- transcription factor
- molecular dynamics
- cell cycle arrest
- cell death
- oxidative stress
- high resolution
- gas chromatography