Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa.
Cristina Lasarte-MonterrubioPablo Arturo Fraile-RibotJuan Carlos Vázquez-UchaGabriel CabotPaula Guijarro-SánchezIsaac Alonso-GarcíaSoraya Rumbo-FealFátima Galán-SánchezAlejandro BeceiroJorge Arca-SuárezAntonio OliverGermán BouPublished in: The Journal of antimicrobial chemotherapy (2022)
Cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam show promising and complementary in vitro activity against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant P. aeruginosa. These agents may represent potential therapeutic options for ceftolozane/tazobactam- and ceftazidime/avibactam-resistant P. aeruginosa infections.