Octreotide ameliorates dermal fibrosis in bleomycin-induced scleroderma

Sibel Oyucu Orhan Ahmet Tektemur Nevzat Gözel İbrahim Hanifi Özercan Servet Yolbas Ahmet Yıldırım Ebru Onalan Etem Suleyman Serdar Koca

Published in: Turkish journal of medical sciences (2018)

Octreotide has antifibrotic actions on experimentally induced dermal fibrosis. It can be suggested that IGF-I plays pathogenic roles, and octreotide is a candidate for research in the treatment of scleroderma.

Keyphrases

high glucose
systemic sclerosis
diabetic rats
neuroendocrine tumors
interstitial lung disease
drug induced
endothelial cells
pulmonary fibrosis
rheumatoid arthritis
mouse model
binding protein
cell proliferation
replacement therapy