Decreased bone marrow regulatory innate lymphoid cells show a distinctive miRNA profiling in aplastic anemia.

Yingmei LiDingming WanRong GuoFang WangLijie HanDanfeng ZhangHaizhou XingWeijie CaoYu LiuXinsheng XieJifeng YuZhongxing Jiang

Published in: Hematology (Amsterdam, Netherlands) (2021)

The present study demonstrated the deficiency of ILCregs and differential expression pattern of ILCregs gene-related miRNA in patients with AA. Further studies need to be done to explore the clinical significance of ILCregs and related miRNAs in patients with AA with large samples size and clinical follow-up.

Keyphrases

bone marrow
induced apoptosis
mesenchymal stem cells
chronic kidney disease
cell cycle arrest
genome wide
transcription factor
single cell
dna methylation
cell death
endoplasmic reticulum stress
signaling pathway
acute myeloid leukemia
acute lymphoblastic leukemia
genome wide identification