Phenotype-independent DNA methylation changes in prostate cancer.

Davide PellacaniAlastair P DroopFiona M FrameMatthew S SimmsVincent M MannAnne G E CollinsConnie J EavesNorman J Maitland

Published in: British journal of cancer (2018)

This study demonstrates the importance of comparing phenotypically matched prostate cell populations from normal and cancer tissues to unmask biologically and clinically relevant DNA methylation changes.

Keyphrases

dna methylation
prostate cancer
gene expression
genome wide
radical prostatectomy
papillary thyroid
single cell
cell therapy
squamous cell
copy number
young adults
childhood cancer