Vitamin D supplementation for children with cancer: A systematic review and consensus recommendations.
Jenneke E van AtteveldIris E VerhagenMarry M van den Heuvel-EibrinkHanneke M van SantenInge M van der SluisNatascia Di IorgiJill H SimmonsLeanne M WardSebastian J C M M NeggersPublished in: Cancer medicine (2021)
There is a lack of evidence for an effect of vitamin D (and calcium) supplementation on BMD or fractures in children with cancer. Further research is needed; until then, we recommend dietary vitamin D/calcium intake in keeping with standard national guidelines, and periodic 25OHD monitoring to detect levels <20 ng/ml. Vitamin D/calcium supplementation is recommended in children with low levels, to maintain levels ≥20 ng/ml year-long.