Quantitative Ultrasound and the Pancreas: Demonstration of Early Detection Capability.
Rita J MillerAiguo HanJohn W ErdmanMatthew A WalligWilliam D O'BrienPublished in: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine (2018)
Cerulein-induced pancreatitis is an excellent model for studying ultrasonic AC and BSC biomarkers during the early stages of acute pancreatitits, reflecting microscopic structural changes. Edema followed by cell shrinkage and apoptosis, then histiocytic infiltration and fibrosis, has certain similarities with the morphologies of some forms of pancreatic carcinoma. This suggests that quantitative ultrasound may be very useful for early detection of disease onset or response to therapy for not only acute pancreatitis but also pancreatic cancer.
Keyphrases
- magnetic resonance imaging
- drug induced
- oxidative stress
- liver failure
- diabetic rats
- single cell
- high glucose
- endoplasmic reticulum stress
- cell therapy
- contrast enhanced ultrasound
- ultrasound guided
- cell death
- respiratory failure
- cell cycle arrest
- aortic dissection
- endothelial cells
- bone marrow
- signaling pathway
- pi k akt