Chondro-protective effects of celastrol on osteoarthritis through autophagy activation and NF-κB signaling pathway inhibition.
Kai FengHongfang ChenChen XuPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)
In summary, celastrol protected against chondrocyte apoptosis by promoting autophagy and inhibiting NF-κB signaling pathway in vitro and in vivo.