Effects of Focal Radiation on [18 F]-Fluoro-D-Glucose Positron Emission Tomography in the Brains of Miniature Pigs: Preliminary Findings on Local Metabolism.
Chun-I YehMei-Fang ChengFuren XiaoYi-Chieh ChenChien-Chu LiuHung-Yi ChenRuoh-Fang YenYu-Ten JuYilin ChenMohan BodduluriPin-Huan YuChau-Hwa ChiNgot Swan ChongLiang-Hsiang WuJohn R AdlerMichael Bret SchneiderPublished in: Neuromodulation : journal of the International Neuromodulation Society (2020)
Focal, noninvasive, and durable changes in brain activity can be induced without a magnetic resonance imaging (MRI)-visible lesion, a result that may be consistent with the occurrence of neuromodulation. This approach may provide new venues for the investigation of neuromodulatory treatments for disorders involving dysfunctional brain circuits. Postmortem pathological analysis is needed to elucidate whether there have been morphological changes not detected by MRI.
Keyphrases
- radiation therapy
- positron emission tomography
- magnetic resonance imaging
- computed tomography
- contrast enhanced
- diffusion weighted imaging
- pet imaging
- pet ct
- risk assessment
- high glucose
- magnetic resonance
- white matter
- diabetic rats
- drug induced
- blood pressure
- oxidative stress
- adipose tissue
- multiple sclerosis
- insulin resistance
- skeletal muscle