Failing the four-gamete test enables exact phasing: the Corners' Algorithm.

Published in: Genetics, selection, evolution : GSE (2022)

The Corner's Algorithm allows to fully phase haplotypes when the four-gamete test fails. Longer haplotypes in chromosomal regions in which the four-gamete test fails for any pair of SNPs can be used as a multi-allelic marker with increased polymorphism information content.

Keyphrases

machine learning
deep learning
healthcare
genome wide
density functional theory
gene expression
copy number
molecular dynamics