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Ling-Gui-Zhu-Gan decoction protects against doxorubicin-induced myocardial injury by downregulating ferroptosis.

Ya-Li YangChuan-Zhi ZhaoChun-Chun ZhaoZhong-Yu WenYao-Yao MaXiao-Ni ZhaoLiang WangJin-Ling HuangPeng Zhou
Published in: The Journal of pharmacy and pharmacology (2024)
LGZGD can ameliorate DOX-cardiotoxicity by activating the Nrf2 signaling pathway and inhibiting ferroptosis in cardiomyocytes.
Keyphrases
  • signaling pathway
  • cell death
  • high glucose
  • pi k akt
  • induced apoptosis
  • epithelial mesenchymal transition
  • oxidative stress
  • diabetic rats
  • endothelial cells
  • drug delivery
  • left ventricular
  • cancer therapy
  • drug induced