α-Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC-SNCA Mice.

Norihito Uemura Jun UedaToru YoshiharaMasashi IkunoMaiko T UemuraHodaka YamakadoMasahide AsanoJohn Q TrojanowskiRyosuke Takahashi

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

Our data suggest that α-Syn spread from the olfactory bulb mainly affects the olfactory pathway and limbic system as well as its related regions, leading to the development of hyposmia, anxiety, and memory loss in PD. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

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