The Characteristics of Patients with Severe COVID-19 Pneumonia Treated with Direct Hemoperfusion Using Polymyxin B-Immobilized Fiber Column (PMX-DHP).

Tsukasa Kuwana Kosaku Kinoshita Shingo IharaNami SawadaToru Hosokawa Tomokazu MutohUmefumi IguchiKatsuhiro NakagawaJunko Yamaguchi

Published in: Infection and drug resistance (2022)

PMX-DHP, in addition to steroids and immunomodulators, may improve oxygenation and alleviate tachypnea by modulating the lymphocyte numbers and levels of various mediator against severe COVID-19 pneumonia. It may be better to perform PMX-DHP before multi organ dysfunction and lung injury has progressed. Furthermore, the early increase in lymphocyte counts after PMX-DHP might be an indicate a positive outcome.

Keyphrases

coronavirus disease
sars cov
peripheral blood
early onset
oxidative stress
respiratory syndrome coronavirus
drug induced
intensive care unit
multidrug resistant
gram negative
newly diagnosed
solid phase extraction
acute respiratory distress syndrome
capillary electrophoresis