Pinning allergies on pathogenic TH2 cells.

Published in: Science translational medicine (2018)

A new proinflammatory subtype of antigen-specific TH2 cell that expresses CD161 emerges as the pathogenic cell type in allergic disease and is deleted during allergen-specific immunotherapy (Wambre et al, this issue).

Keyphrases

induced apoptosis
cell cycle arrest
allergic rhinitis
single cell
cell therapy
cell death
oxidative stress
signaling pathway
atopic dermatitis