Impairment of vascular strain in patients with obstructive sleep apnea.
Max Jonathan StumpfChristian Alexander SchaeferJan KryckiRobert SchuelerCarmen PizarroGeorg NickenigMartin SteinmetzDirk SkowaschIzabela Dorota TuletaPublished in: PloS one (2018)
Patients with OSA show significantly reduced vascular strain assessed by ultrasound-based speckle-tracking. Vascular stiffness increases with the severity of the disease. Target vessels to assess vascular strain in patients with OSA are common carotid arteries, whereas other sites of the arterial tree are not reliable. No significant impact of current statin therapy on vascular strain was found. Further studies are needed to evaluate potential benefit of statins in secondary prevention of atherosclerosis in OSA.