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Micro-anatomic alterations of the placenta in a non-human primate model of gestational protein-restriction.

James A SargentVictoria RobertsKaren D'SouzaAdam WrightJessica GaffneyAntonio Frias
Published in: PloS one (2020)
In this pilot study, a gestational protein-restriction diet altered the placental micro-vasculature with decreased vascular caliber and density, which may be related to the observed adverse pregnancy outcomes and perturbed placental perfusion previously demonstrated in this model.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • weight gain
  • endothelial cells
  • protein protein
  • physical activity
  • weight loss
  • binding protein
  • birth weight
  • emergency department
  • body mass index
  • induced pluripotent stem cells