Effects of an Antioxidant-enriched Multivitamin in Cystic Fibrosis. A Randomized, Controlled, Multicenter Clinical Trial.
Scott D SagelUmer KhanRaksha JainGavin GraffCori L DainesJordan M DunitzDrucy BorowitzDavid M OrensteinIbrahim AbdulhamidJulie NoeJohn P ClancyBonnie SlovisMichael J RockKaren S McCoySteven StrausbaughFloyd R LivingstonKonstantinos A PapasMichele L ShafferPublished in: American journal of respiratory and critical care medicine (2019)
Antioxidant supplementation was safe and well tolerated, resulting in increased systemic antioxidant concentrations and modest reductions in systemic inflammation after 4 weeks. Antioxidant treatment was also associated with a lower risk of first pulmonary exacerbation. Clinical trial registered with www.clinicaltrials.gov (NCT01859390).