Dosage compensation and sex-specific epigenetic landscape of the X chromosome in the pea aphid.
Gautier RichardFabrice LegeaiNathalie Prunier-LetermeAnthony BretaudeauDenis TaguJulie JaquiéryGaël Le TrionnairePublished in: Epigenetics & chromatin (2017)
Our results suggest the existence of an underlying epigenetic mechanism enhancing the X chromosome chromatin accessibility in males to allow X-linked gene dose correction between sexes in the pea aphid, similar to Drosophila. Our study gives new evidence into the comprehension of dosage compensation in link with chromatin biology in insects and newly in a major crop pest, taking benefits from both transcriptomic and open chromatin data.