Leukotriene B4: A potential mediator and biomarker for cardiac allograft vasculopathy.

Dong WangGrigol TediashviliDaniel KimXiaomeng HuHelen LuikartThomas RenneAmy TianKari C NadeauJoachim VeldenSonja SchrepferKiran K Khush

Published in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (2024)

This study provides key evidence supporting the role of the inflammatory cytokine LTB4 as an important mediator of CAV development and provides preliminary data suggesting the clinical benefit of Bestatin for CAV prevention.

Keyphrases

oxidative stress
left ventricular
electronic health record
heart failure
machine learning
human health
deep learning
climate change