DNA methylation and histone post-translational modification stability in post-mortem brain tissue.

Jessica S JarmaszHannah StirtonJames R DavieMarc R Del Bigio

Published in: Clinical epigenetics (2019)

We conclude that global epigenetic studies on human post-mortem brain tissue are feasible, but great caution is needed for selection of post-mortem delay matched controls if histone acetylation is of interest.

Keyphrases

dna methylation
gene expression
genome wide
endothelial cells
resting state
copy number
induced pluripotent stem cells
multiple sclerosis