Cuproptosis: Mechanisms, biological significance, and advances in disease treatment-A systematic review.
Chengliang PanZhilin JiQingxuan WangZhao ZhangZhenchuan WangChen LiShan LuPeng-Fei GePublished in: CNS neuroscience & therapeutics (2024)
The study highlights the need for further research to explore alternative pathways of copper-induced cell death, detailed mechanisms of cuproptosis, and biomarkers for copper poisoning. Future research should focus on exploring the molecular mechanisms of cuproptosis, developing new therapeutic strategies, and verifying their safety and efficacy in clinical trials.