Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy.
Bing QinMengshi JiangXiang LiYingying ShiJunlei ZhangZhenyu LuoLihua LuoYichao LuXu LiuSijie WangYongzhong DuYunqing QiuYan LouJian YouPublished in: Journal of nanobiotechnology (2021)
This work was the first attempt to utilize an oxygen nanocarrier to assist the therapeutic effect of gene therapy under hypoxia, providing a new reference for gene therapy in malignant tumors. GRAPHICAL ABSTARCT.