Profiling the molecular and clinical landscape of glioblastoma utilizing the Oncology Research Information Exchange Network brain cancer database.
Alexandra N DemetriouFrances ChowDavid W CraigMichelle G WebbD Ryan OrmondJames BattisteArnab ChakravartiHoward ColmanJohn L VillanoBryan P SchneiderJames K C LiuMichelle L ChurchmanGabriel ZadaPublished in: Neuro-oncology advances (2024)
Herein, we report the first clinical, genomic, and transcriptomic analysis of ORIEN glioblastoma cases, incorporating sample reclassification under updated 2021 diagnostic criteria. These findings create multiple avenues for further investigation and reinforce the value of multi-institutional consortia such as ORIEN in deepening our knowledge of intractable diseases such as glioblastoma.