Influence of extracellular volume fraction on peak exercise oxygen pulse following thoracic radiotherapy.
Justin M CanadaElisabeth WeissJohn D GrizzardCory R TrankleLeila Rezai GharaiFranklin DanaLeo F BuckleySalvatore CarboneDinesh KadariyaAnthony RiccoJennifer H JordanRonald K EvansRyan S GartenBenjamin W Van TassellW Gregory HundleyAntonio AbbatePublished in: Cardio-oncology (London, England) (2022)
Pulse is inversely associated markers of diffuse fibrosis (ECVF), ventricular wall stress (NTproBNP), radiotherapy heart dose, and positively related to LV function. Increased LV ECVF may reflect a potential etiology of impaired LV SV reserve in patients receiving thoracic radiotherapy for chest malignancies.
Keyphrases
- early stage
- locally advanced
- radiation induced
- radiation therapy
- spinal cord
- blood pressure
- heart failure
- rectal cancer
- squamous cell carcinoma
- high intensity
- physical activity
- left ventricular
- low grade
- atrial fibrillation
- stress induced
- human health
- resistance training
- climate change
- body composition
- catheter ablation