Qualitative Analysis of Acid Salts with Direct Analysis in Real Time Mass Spectrometry by Conversion to the Free Acid Form.

Organic acid salts typically have very low volatility and are not well suited for analysis by Direct Analysis in Real Time mass spectrometry (DART-MS). However, qualitative analysis of organic acid salts by DART can be facilitated by the addition of a strong acid to convert the compounds to the free acid form. Examples are presented here for inorganic salts (sodium and potassium perchlorate) and several organic salts, including three disodium salts and a mixed sodium/potassium salt.