Arg399Gln substitution in XRCC1 as a prognostic and predictive biomarker for prostate cancer: Evidence from 8662 subjects and a structural analysis.

Mahdi NoureddiniNarges MobasseriMohammad KarimianMohaddeseh BehjatiHossein Nikzad

Published in: The journal of gene medicine (2018)

Based on these results, the XRCC1-Arg399Gln polymorphism might be a risk factor for PCa and it could be considered as a prognostic and predictive biomarker for susceptible men.

Keyphrases

prostate cancer
dna repair
radical prostatectomy
dna damage