Ti(OiPr)4-Facilitated Formal Deoxygenative Annulation of Alkynyl 1,2-Diketones for the Synthesis of Highly Functionalized Furans.

Shouang LanRui LiuXiangwen KongJinggong LiuBenlong LuoShuang YangXinqiang Fang

Published in: Organic letters (2021)

A unique deoxygenative cyclodimerization of alkynyl 1,2-diketones facilitated by Ti(OiPr)4 is achieved, affording a series of highly functionalized furan products. An unusual C-C bond and C═O bond cleavage of the substrates is observed, and Ti(OiPr)4 plays triplicate roles in the reaction. Furthermore, the products show uncommon fluorescent emission in the solid state, indicating the potential practical applications of this work.

Keyphrases

solid state
quantum dots
molecularly imprinted
electron transfer
living cells
transition metal
high resolution