Maternal apical periodontitis is associated with insulin resistance in adult offspring.
Thaís Verônica Saori TsosuraF Y ChibaM S L C MatteraR F PereiraLuciano Tavares Angelo CintraL C ContiRodrigo Martins Dos SantosJ H P MateusC A S GarbinD H SumidaPublished in: International endodontic journal (2019)
Maternal AP was associated with insulin resistance in adult offspring through alterations in insulin signalling and inflammation pathways. The study provides information on the impact of maternal AP on the development of metabolic alterations such as insulin resistance in adult offspring and reinforces the importance of preventing maternal AP in order to maintain the general health of offspring.