Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway.
Xi HuangHang YuCong XieYao-Long ZhouMeng-Meng ChenHan-Lin ShiWei-Feng TangJing-Cheng DongQing-Li LuoPublished in: Pharmaceutical biology (2022)
LKZP improves lung function, airway inflammation, mucus secretion and correct immune imbalance by intervening with the IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway, presenting a promising therapeutic choice for asthma.
Keyphrases
- lung function
- signaling pathway
- pi k akt
- cell proliferation
- chronic obstructive pulmonary disease
- cystic fibrosis
- air pollution
- lps induced
- liver failure
- oxidative stress
- respiratory failure
- nuclear factor
- high fat diet induced
- inflammatory response
- aortic dissection
- adipose tissue
- skeletal muscle
- intensive care unit
- decision making
- insulin resistance