Validity of pathological diagnosis for early colorectal cancer in genetic background.
Kenichiro OkimotoYosuke HirotsuMakoto AraiKenji AmemiyaNaoki AkizueYuki OhtaTakashi TaidaKeiko SaitoHiroshi OhyamaTomoaki MatsumuraMotoi NishimuraKazuyuki MatsushitaKeisuke MatsusakaToshio OyamaHitoshi MochizukiTetsuhiro ChibaJun KatoJun-Ichiro IkedaOsamu YokosukaNaoya KatoMasao OmataPublished in: Cancer medicine (2023)
In conclusion, the definition of E-CRC according to the Japanese criteria had a different genetic profile from CRA and was more similar to AD-CRC. Based on the main pathway, it seemed reasonable to classify E-CRC as adenocarcinoma. The pathological diagnosis of E-CRC according to Japanese definition seemed to be valid from a genetic point of view.