Prognostic Relevance of Pancreatic Adenocarcinoma Whole-Tumor Transcriptomic Subtypes and Components.

Shulin ZhaoRémy NicolleJérémy AugustinMagali SvrcekLouis de MestierDelphine Le CorreDaniel PietraszOlivier CaliezJérôme CrosPierre Laurent-PuigJean-Baptiste Bachet

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

We described the advantage of the prognostic value and robustness of the whole-tumor transcriptomic components than subtypes. We created and validated a new DFS-based multivariate Cox regression prognostic model, including six pancreatic adenocarcinoma transcriptomic component levels and pathologic characteristics.

Keyphrases

single cell
rna seq
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
lymph node
locally advanced
data analysis
rectal cancer