Causal effect of severe and non-severe malaria on dyslipidemia in African Ancestry individuals: A Mendelian randomization study.
Mariam TraoreHarouna SangareOudou DiabateAbdoulaye DiawaraCheickna CisséOyekanmi NashiruJian LiJeffrey ShafferMamadou WéléSeydou DoumbiaTinashe ChikoworeOpeyemi SoremekunSegun FatumoPublished in: Annals of human genetics (2024)
Our findings challenge the hypothesis of a broad causal relationship between malaria (both severe and recurrent non-severe forms) and dyslipidemia. The isolated association with SMA highlights an intriguing area for future research. However, we believe that conducting larger studies to investigate the connection between malaria and dyslipidemia in Africa will enhance our ability to better address the burden posed by both diseases.