Evaluation of circulating Dickkopf-1 as a prognostic biomarker in ovarian cancer patients.
Daniel Martin KlotzTheresa LinkMaren GoeckenjanPauline WimbergerAnna R PoetschNikolai JaschkeLorenz C HofbauerAndy GöbelTilman D RachnerJan Dominik KuhlmannPublished in: Clinical chemistry and laboratory medicine (2021)
This is the first study demonstrating the prognostic relevance of sDKK1 in ovarian cancer patients, including those with wtBRCA 1/2 status. Our data encourage further evaluation of sDKK1 in ovarian cancer patients, possibly in terms of a therapy monitoring marker or a response predictor for sDKK1-directed targeted therapies.