Recent advances in understanding Pseudomonas aeruginosa as a pathogen.
Jens KlockgetherBurkhard TümmlerPublished in: F1000Research (2017)
The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection.
Keyphrases
- pseudomonas aeruginosa
- biofilm formation
- type iii
- candida albicans
- cystic fibrosis
- endothelial cells
- acinetobacter baumannii
- liver failure
- drug induced
- staphylococcus aureus
- respiratory failure
- escherichia coli
- metabolic syndrome
- cardiovascular disease
- weight loss
- physical activity
- induced pluripotent stem cells
- type diabetes
- intensive care unit
- drug resistant
- multidrug resistant