A Machine-Learning Derived Huntington's Disease Progression Model: Insights for Clinical Trial Design.
Amrita MohanZhaonan SunSoumya GhoshYing LiSwati SatheJianying HuCristina SampaioPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
The natural history of Huntington's disease can be described by nine disease states of increasing severity. The ability to derive characteristics of disease states and probabilities for progression through these states will improve trial design and participant selection. © 2021 International Parkinson and Movement Disorder Society.