Isolation of a high-affinity Bet v 1-specific IgG-derived ScFv from a subject vaccinated with hypoallergenic Bet v 1 fragments.

E GadermaierK MarthC LupinekR CampanaG HoferK BlattDubravka SmiljkovicU RoderM Focke-TejklS VrtalaWalter KellerP ValentRudolph Valenta Sabine Flicker

Published in: Allergy (2018)

Immunization with unfolded hypoallergenic allergen derivatives induces high-affinity antibodies even in nonallergic subjects which recognize the folded wild-type allergens and inhibit polyclonal IgE binding of allergic patients.

Keyphrases

wild type
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
allergic rhinitis
patient reported outcomes
patient reported