Satellite-Based Sensor for Environmental Heat-Stress Sweat Creatinine Monitoring: The Remote Artificial Intelligence-Assisted Epidermal Wearable Sensing for Health Evaluation.
Surachate KalasinPantawan SangnuangWerasak SurareungchaiPublished in: ACS biomaterials science & engineering (2020)
Wearable human sweat sensors have offered a great prospect in epidermal detection for self-monitoring and health evaluation. These on-body epidermal sensors can be integrated with the Internet of Things (IoT) as augmented diagnostics tools for telehealth applications, especially for noninvasive health monitoring without using blood contents. One of many great benefits in utilizing sweat as biofluid is the capability of instantaneously continuous diagnosis during normal day-to-day activities. Here, we revealed a textile-based sweat sensor selective for perspired creatinine that is prepared by coating poly(vinyl alcohol) (PVA)-Cu2+-poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS) and cuprous oxide nanoparticles on stretchable nylon, is equipped with heart rate monitoring and a satellite-communication device to locate wearers, and incorporates machine learning to predict the levels of environmental heat stress. Electrochemical impedance spectroscopy (EIS) was used to investigate different charge-transfer resistances of PVA and PEDOT:PSS with cuprous and cuprite ions induced by single-chain and ionic cross-linking. Furthermore, density function theory (DFT) studies predicted the catalytic binding of sweat creatinine with the sensing materials that occurred at thiophene rings. The hybrid sensor successfully achieved 96.3% selectivity efficacy toward the determination of creatinine contents from 0.4 to 960 μM in the presence of interfering species of glucose, urea, uric acid, and NaCl as well as retained 92.1% selectivity efficacy in the existence of unspecified human sweat interference. Ultimately, the hand-grip portable device can offer the great benefit of continuous health monitoring and provide the location of any wearer. This augmented telemedicine sensor may represent the first remote low-cost and artificial-intelligence-based sensing device selective for heat-stress sweat creatinine.
Keyphrases
- heat stress
- artificial intelligence
- uric acid
- machine learning
- heart rate
- low cost
- public health
- big data
- healthcare
- metabolic syndrome
- deep learning
- heat shock
- health information
- mental health
- endothelial cells
- blood pressure
- human health
- heart rate variability
- gold nanoparticles
- computed tomography
- adipose tissue
- skeletal muscle
- label free
- social media
- mass spectrometry
- wound healing
- single cell
- molecular docking
- tandem mass spectrometry
- virtual reality
- solid phase extraction
- risk assessment
- single molecule