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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature.

Ryo MiyagiToshihiko NishishoShinjiro TakataYoshimitsu ShimataniShunichi TokiKoichi Sairyo
Published in: Case reports in orthopedics (2017)
We encountered a huge atypical tumor in a patient with MD. This is the first detailed report to describe an association between ALT and MD. We hypothesize that degenerative changes occurring in adipose tissue during muscle atrophy can cause lipomatous neoplasms and moreover that the mutation of MD-related genes may lead to the proliferation of tumor cells or to malignancy.
Keyphrases
  • muscular dystrophy
  • adipose tissue
  • molecular dynamics
  • case report
  • multiple sclerosis
  • skeletal muscle
  • high fat diet
  • insulin resistance