Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity.

Mark SorinElham KarimiMorteza RezanejadMiranda W YuLysanne DesharnaisSheri A C McDowellSamuel DoréAzadeh ArabzadehValerie BretonBenoit FisetYuhong WeiRoni RayesMichele OrainFrancois CoulombeVenkata S K ManemAndreanne GagneDaniela F QuailPhilippe JoubertJonathan D SpicerLogan A Walsh

Published in: Journal for immunotherapy of cancer (2023)

Our results provide a high-resolution molecular resource and illustrate the importance of major immune lineages as well as their functional substates in understanding the role of the tumor immune microenvironment in response to ICIs.

Keyphrases

single cell
high resolution
rna seq
stem cells
high throughput
single molecule