Phase Angle Is a Stronger Predictor of Hospital Outcome than Subjective Global Assessment-Results from the Prospective Dessau Hospital Malnutrition Study.
Mathias PlauthIsabella SulzMelanie ViertelVeronika HöferMila WittFrank RaddatzMichael ReichMichael HiesmayrPeter BauerPublished in: Nutrients (2022)
This prospective cohort study of 16,943 consecutive patients compared phase angle (PhA, foot-to-hand at 50 kHz) and subjective global assessment (SGA) to predict outcomes length of hospital stay (LOS) and in-hospital mortality in patients at risk of malnutrition (NRS-2002 ≥ 3). In 1505 patients, the independent effects on LOS were determined by competing risk analysis and on mortality by logistic regression. In model I, including influence factors age, sex, BMI, and diagnoses, malnourished (SGA B and C) patients had a lower chance for a regular discharge (HR 0.74; 95%CI 0.69-0.79) and an increased risk of mortality (OR 2.87; 95%CI 1.38-5.94). The association of SGA and outcomes regular discharge and mortality was completely abrogated when PhA was added (model II). Low PhA reduced the chance of a regular discharge by 53% in patients with a PhA ≤ 3° (HR 0.47; 95%CI 0.39-0.56) as compared to PhA > 5°. Mortality was reduced by 56% for each 1° of PhA (OR 0.44; 95%CI 0.32-0.61). Even when CRP was added in model III, PhA ≤ 3° was associated with a 41% lower chance for a regular discharge (HR 0.59; 95%CI 0.48-0.72). In patients at risk of malnutrition, the objective measure PhA was a stronger predictor of LOS and mortality than SGA.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- healthcare
- cardiovascular events
- newly diagnosed
- peritoneal dialysis
- risk factors
- emergency department
- high resolution
- body mass index
- metabolic syndrome
- depressive symptoms
- adipose tissue
- cardiovascular disease
- skeletal muscle
- high frequency
- adverse drug
- coronary artery disease
- sleep quality
- patient reported