Chiral Dinuclear Vanadium Complex-Mediated Oxidative Coupling of Resorcinols.
Makoto SakoTakanori AokiNadine ZumbrägelLukas SchoberHarald GrögerShinobu TakizawaHiroaki SasaiPublished in: The Journal of organic chemistry (2018)
A method for the highly regio- and enantioselective oxidative coupling of resorcinols has been established by using dibrominated dinuclear vanadium(V) catalyst 1c under air. When resorcinols bearing an aryl substituent were applied as substrates to the coupling, axially chiral biresorcinols were obtained as single regioisomers in high yield with up to 98% ee.