Methylsulfonylmethane induces caspase-dependent apoptosis in acute myeloid leukemia cell lines.

Yalda Hekmatshoar Arzu Zeynep KarabayTulin OzkanAsli KocAsuman Sunguroglu

Published in: Fundamental & clinical pharmacology (2024)

Overall, our results indicated that MSM could induce apoptosis in AML cell lines in a dose-dependent manner, which therefore could be utilized as an antileukemic agent.

Keyphrases

cell death
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
induced apoptosis
acute myeloid leukemia
pi k akt
allogeneic hematopoietic stem cell transplantation
acute lymphoblastic leukemia
hepatitis c virus
hiv infected