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Regional [18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer's disease.

Emma E WoltersRik OssenkoppeleSander C J VerfaillieEmma M CoomansTessa TimmersDenise VisserHayel TuncelSandeep S V GollaAlbert D WindhorstRonald BoellaardWiesje M van der FlierCharlotte E TeunissenPhilip ScheltensBart N M van Berckel
Published in: European journal of nuclear medicine and molecular imaging (2020)
Regional [18F]flortaucipir BPND correlated stronger with cognition and neurodegeneration than CSF p-tau, suggesting that tau PET more accurately reflects disease severity in AD.
Keyphrases
  • cerebrospinal fluid
  • pet ct
  • positron emission tomography
  • computed tomography
  • pet imaging
  • cognitive decline
  • mild cognitive impairment
  • white matter