Regional [18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer's disease.
Emma E WoltersRik OssenkoppeleSander C J VerfaillieEmma M CoomansTessa TimmersDenise VisserHayel TuncelSandeep S V GollaAlbert D WindhorstRonald BoellaardWiesje M van der FlierCharlotte E TeunissenPhilip ScheltensBart N M van BerckelPublished in: European journal of nuclear medicine and molecular imaging (2020)
Regional [18F]flortaucipir BPND correlated stronger with cognition and neurodegeneration than CSF p-tau, suggesting that tau PET more accurately reflects disease severity in AD.