S-methyl cysteine sulfoxide mitigates histopathological damage, alleviate oxidative stress and promotes immunomodulation in diabetic rats.

Licyanne Ingrid C LemosMatheus Anselmo MedeirosJoão Paulo Matos Santos Lima Tatiane O Teixeira Camila Alexandrina Viana de Figueiredo Naisandra B S FariasFlavio S SilvaBento João Abreu Karina Carla P Medeiros Lucia de Fatima Campos Pedrosa

Published in: Journal of complementary & integrative medicine (2021)

Oral treatment of SMCS showed improvement of the morphological alterations in liver and pancreatic islet in diabetic rats. These beneficial morphological effects of SMCS can be partially explained by IL-10 modulation associated with antioxidant action.

Keyphrases

diabetic rats
oxidative stress
ischemia reperfusion injury
dna damage
induced apoptosis
radiation therapy
combination therapy
living cells