Identification of Heterogeneous Cognitive Subgroups in Community-Dwelling Older Adults: A Latent Class Analysis of the Einstein Aging Study.

Andrea R ZammitCharles B HallRichard B LiptonMindy J KatzGraciela Muniz-Terrera

Published in: Journal of the International Neuropsychological Society : JINS (2018)

LC modeling in a community sample of older adults revealed 9 cognitive subgroups. Assignment of subgroups was reliable and associated with external validators. Future work will test the predictive validity of these groups for outcomes such as Alzheimer's disease, vascular dementia and death, as well as markers of biological pathways that contribute to cognitive decline. (JINS, 2018, 24, 511-523).

Keyphrases

cognitive decline
mild cognitive impairment
healthcare
mental health
physical activity
single cell
current status
mass spectrometry
simultaneous determination
adipose tissue
high resolution
skeletal muscle
insulin resistance