Possible association of sialolithiasis with HIV infection and highly active antiretroviral therapy: A case report.
John K BrooksJoyce L JonesJeffery B PricePublished in: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (2020)
Although there appears to be an overall trend of diminishing oral manifestations of HIV infection, evidence is emerging on the increased incidence of concomitant parotid gland enlargement and xerostomia. Furthermore, several case narrations and a limited series have suggested a possible association of sialolithiasis with highly active antiretroviral therapy, mostly involving the parotid gland. The aim of this report is to present a patient with a giant sialolith of the submandibular gland following a 27-year intake of various antiretrovirals for HIV infection and review the relevant literature.