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DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells.

Aurelie VanderlindenCallum G JonesKatie N MyersOla RominiyiSpencer James Collis
Published in: British journal of cancer (2023)
To our knowledge, our findings represent the first report of TTFields applied with clinically approved or in-trial DDRi in GSC models and provides a basis for translational studies toward multimodal DDRi/TTFields-based therapeutic strategies for patients with these currently incurable tumours.
Keyphrases
  • dna damage response
  • dna repair
  • healthcare
  • study protocol
  • clinical trial
  • phase iii
  • phase ii
  • case control
  • drug administration
  • dna damage
  • oxidative stress