Cystic fibrosis newborn screening in Switzerland - evaluation and scenarios for improvement after 11 years of follow-up.
Esl PedersenC M de Jong CarmenM JurcaD O BergerJ SanzShm SlukaM PomsM R BaumgartnerN RegameyC E KuehniJ BarbenC S Rueeggnull nullPublished in: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society (2024)
The Swiss CF-NBS program performed well over 11 years but did not achieve the ECFS standards for PPV (≥30 %). Modifying or removing the safety net could improve PPV and reduce unnecessary follow-up tests while maintaining the ECFS standards for sensitivity.